Effect of anti-mullerian hormone, FSH and LH in evaluating ovarian reserve after laparoscopy surgery

Laparoscopy has become the primary choice for common ovarian surgery. This study recruited patients undergone ovarian laparoscopy surgery in our hospital, and measured their anti-mullerian hormone (AMH), follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels, in order to analyze their correlation with ovarian reserve functions. Ovarian cysts patients, including chocolate cysts group and non-chocolate cysts were recruited as the experimental group, in addition to healthy individuals as the control group. At different time points (2 days before surgery, 2 days after surgery, and 3 months after surgery), AMH, FSH and LH levels were quantified. The ovarian volume (V), peak systolic velocity (PSV) of ovarian intestinal artery, and antral follicles count (AFC) were measured by colored ultrasonography 3 months after surgery. AMH, FSH and LH levels were higher in disease group at all time points compared to control group (P<0.05). The levels of AMH, FSH and LH were decreased in patient group 2 days after surgery compared to those before surgery, and were slightly increased 3 months later. No significant difference has been observed between unilateral chocolate cyst and non-chocolate cyst patients regarding hormone levels (P>0.05) while bilateral chocolate cyst patients had more significant changes (P<0.05). After surgery, V and PSV were similar against control group while AFC was remarkably decreased (P<0.05). Levels of AMH, FSH and LH were decreased after ovarian laparoscopy, accompanied with decreased AFC, all of which indicated injury on ovarian reserve.